Recombinant Molecules for a Healthy Society

By Icy D’Silva.

Published by The International Journal of Health, Wellness and Society

Format Price
Article: Print $US10.00
Article: Electronic $US5.00

Recombinant molecules, such as nucleic acids or proteins, including antibodies, antigens, cytokines, enzymes, growth factors and hormones are generated by identifying, isolating and transferring the gene of interest from one organism into the plasmid of another/host organism. The controlled creation of novel functional recombinant molecules is essential for a variety of purposes, including food safety, safe environment, and personalized medicine. Recombinant chymosin was the first recombinant enzyme produced to replace native rennet in cheese making. Recombinant antibodies are robust, reliable, sensitive and rapid biosensor-based detectors of food pathogens. As a research study, among the recombinant ovalbumin and recombinant ovalbumin mutant proteins that were designed, developed, tested and studied for their protective efficiency against egg allergy in a mouse model, a double mutant and a triple mutant were effective in completely preventing anaphylaxis. These recombinant ovalbumin mutants are promising molecules for potential use as substitutes for native ovalbumin in food products, as key reference proteins replacing native ovalbumin in laboratories, and as therapeutics against native ovalbumin in medicine. This theoretical discourse presents an overview of recombinant molecules for food safety, improved nutrition, personal wellness, personalized medicine, safe environment, better quality of life, and thereby for a healthy society.

Keywords: Food Safety, Healthy Society, Recombinant Molecules

The International Journal of Health, Wellness and Society, Volume 1, Issue 2, pp.219-226. Article: Print (Spiral Bound). Article: Electronic (PDF File; 717.152KB).

Icy D’Silva

PhD Graduating Student, Department of Food Science, Ontario Agricultural College, University of Guelph, Guelph, Ontario, Canada

Icy D’Silva (Ida Iris Icy D’Silva) earned her Master of Science degree studying “Anti-Lipopolysaccharide Antibody- Mediated Disease Resistance against Pseudomonas aeruginosa O6ad in Tobacco” with Professor J. Christopher Hall as her Mentor and Advisor, from the University of Guelph (Canada) renowned for its excellence in teaching, research and innovation. Icy is a Doctor of Philosophy Graduate at the University of Guelph having been involved in the study of recombinant molecules towards resistance against egg allergy with Professor Yoshinori Mine as Advisor and Professor J. Christopher Hall as her Mentor. Her expertise in biology has been widely chronicled and she has contributed to a number of academic journals, articles and book chapters. Icy has been enthusiastically participating in innumerable opportunities offered by the University of Guelph. Icy has been a University of Guelph - Ontario Agricultural College - Graduate Student Senator, and a University of Guelph - Food Science Department - Graduate Students’ Representative. Icy is equally active in serving the Guelph and Canadian community in particular, as well as the World community at large. Icy is an avid reader and writer.